Unidimensional Thin Layer Chromatography of Salicylic Acid Derivatives on Boric Acid-Impregnated Plates in Drugs Studies

unidimensional thin layer chromatography of salicylic acid derivatives on boric acid-impregnated plates in drugs studies

Unidimensional thin-layer chromatography of phospholipids on boric acid-impregnated plates.

A unidimensional thin-layer chromatography system for the separation of phospholipids has been developed. The method employs precoated plates impregnated with boric acid and is capable of resolving eight phospholipid standards, including phosphatidylinositol, phosphatidylserine, and phosphatidylglycerol. Liver, kidney, and platelet phospholipids of the rat were resolved into six major classes u...

Equilibrium studies on chromium(III) complexes of salicylic acid and salicylic acid derivatives in aqueous solution.

The complexes of chromium(III) ion formed by salicylic acid, SA(H(2)L), and its derivatives (H(2)L): 5-nitrosalicylic acid (5-NSA), 5-sulphosalicylic acid (5-SSA) were investigated by means of potentiometry and spectroscopy, at 25 degrees C and in ionic strength of 0.1 M KNO(3) and 0.1 M KCl, respectively. Over the acidic pH range, the coordination of Cr(III) ion to SA and its derivatives in 1 ...

Separation of Vitamin B2 and B12 byImpregnate HPTLC Plates with Boric Acid

A high performance thin layer chromatography system (HPTLC) for the separation of vitamin B2 and B12 has been developed. The separation was successfully using a solvent system of methanol, water, ammonia 7.3.1 (V/V) as mobile phase on HPTLC plates impregnated with boric acid. The effect of other mobile phases on the separation of vitamins was also examined. The method is based on different beha...

Changes in Fatty Acid Composition during Preparative Thin-layer Chromatography.

n Thin-layer chromatography (TLC) is being used increasingly for the separation of the lipid classes (1, 2) prior to the analysis of their fatty acids by gas-liquid chromatography (GLC). Malins and Mangold (3) have described the separation of the methyl esters of fatty acids of menhaden oil from other lipid constituents and stated “the gas chromatogram of the total methyl ester fraction agreed ...

Thin-layer chromatography of anticonvulsant drugs.

A rapid semiquantitative method for the determination of anticonvulsant drugs in blood and urine by thin-layer chromatography is described that is applicable in most laboratories.Utilization of SilicAR TLC-7GF with benzene:acetone (4:1), chloroform:acetone(9:1), and carbontetrachloride:acetone(7:3) providesseparationof Dilantin,phenobarbital, Mysoline,Phenylethylmalondiamide, Mesantoin,and Nirv...